You are viewing Allergic Living Canada | Switch to United States

Talking Allergies

* FAQ    * Search
* Login   * Register
It is currently Mon Oct 20, 2014 5:52 am

All times are UTC - 4 hours




Post new topic Reply to topic  [ 1 post ] 
Author Message
PostPosted: Thu Nov 12, 2009 7:28 am 
Offline

Joined: Thu Dec 20, 2007 7:23 pm
Posts: 823
Location: Kingston
Quote:
Researchers at the University of Newcastle and the Cooperative Research Centre (CRC) for Asthma and Airways have made a major breakthrough that has the potential to revolutionise the treatment of asthma and potentially other inflammatory diseases.

Professor Paul Foster, Associate Professor Joerg Mattes and a team of young CRC scientists in the Hunter have discovered for the first time a way to stop inflammation, the main cause of asthma and other chronic diseases, by blocking malfunctioning microRNA molecules.

MicroRNA molecules regulate protein production in human cells. When the molecules malfunction they cause an imbalance in protein levels leading to an inflammation in the body. This inflammation can manifest as asthma, rheumatoid arthritis or a number of other conditions.

"Based on the understanding that malfunctioning MicroRNA molecules may lead to asthma or other types of inflammation, our research team has been looking at ways to inhibit their function," Professor Foster said.

"The research team has established in an asthma model for the first time that the effect of a malfunctioning microRNA can be blocked with a specific chemical (antagomir) treatment."

Current therapies use inhaled steroids to suppress the inflammatory response and relieve asthma symptoms. Long term use of steroids can be harmful.

"Our major discovery opens up a number of exciting pathways using a direct intervention at the molecular level to treat inflammatory conditions such as asthma and potentially other inflammatory diseases such as rheumatoid arthritis," he said.

"Essentially we are developing new possibilities to treat the cause rather than just the symptoms."

The next step is to replicate the testing with human tissue.


http://www.sciencealert.com.au/news/20091211-20220.html

_________________
Mary


Top
 Profile  
 
Display posts from previous:  Sort by  
Post new topic Reply to topic  [ 1 post ] 

All times are UTC - 4 hours


Who is online

Users browsing this forum: No registered users and 2 guests


You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot post attachments in this forum

Search for:
Jump to:  
cron
Powered by phpBB® Forum Software © phpBB Group