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PostPosted: Thu Feb 28, 2013 8:33 am 
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Joined: Thu Dec 20, 2007 7:23 pm
Posts: 827
Location: Kingston
Quote:
For children with peanut allergies, starting oral tolerance therapy while they are still toddlers may be beneficial, researchers said here.

Among 41 children from 16- to 37-months-old, oral immunotherapy lasting up to 3 years using low doses of peanut protein led to decreases in mast cell responsiveness and peanut-specific IgE levels as well as increases in anti-allergic IgG4 levels, according to interim results reported by Brian Vickery, MD, of the University of North Carolina (UNC) in Chapel Hill.

Moreover, in the first 12 children to achieve the ability to tolerate 5 grams of peanut protein, subsequent blinded oral challenges 1 month apart were successful in all 12, Vickery told attendees at the American Academy of Allergy, Asthma, and Immunology (AAAAI) annual meeting.

This was the first oral immunotherapy study in food allergy to be conducted exclusively in toddlers, he said, and in some ways among the most successful in any age group.


http://www.medpagetoday.com/MeetingCoverage/AAAAI/37564

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