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PostPosted: Wed Jul 04, 2012 6:47 am 
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Joined: Thu Dec 20, 2007 7:23 pm
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Location: Kingston
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An insurance claims database was the source of data for Schumock's study. He and his research team found 344 cases of attempted suicide from a group of 195,000 five- to 24-year-olds taking asthma medications.

According to the research, the suicidal group had increased rates of substance abuse, bipolar disease, depression, schizophrenia, and epilepsy, among other illnesses. The subjects also were being treated with additional medications such as antidepressants, antipsychotics, and anticonvulsants. After accounting for these factors, Schumock and his colleagues found no increased risk for suicide among those taking LTMAs compared to other asthma medications.

Among cases, 5.5 percent were using LTMAs at the time of their suicide attempt, compared with 6.5 percent who had not tried to commit suicide. All but five of the subjects were taking montelukast, with the remaining taking zafirlukast. No cases were reported using zileuton, Schumock said.

The research focused on children, adolescents, and young adults. In these patients LTMAs are an important treatment option because these medications can be taken orally, whereas other asthma drugs are inhaled and can be difficult for children to administer, he said.

"While there still needs to be additional research, physicians who treat kids with LTMAs may feel more comfortable now if there was any hesitation before," Schumock said.

Schumock said the research suggested an increased risk of suicide in young adults ages 19 to 24 who used LTMAs, but the finding was not statistically significant. Further research needs to be conducted in that age group and in adults, he said.


http://www.healthcanal.com/mental-healt ... empts.html

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