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PostPosted: Tue Jul 10, 2012 8:17 pm 
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Joined: Thu Dec 20, 2007 7:23 pm
Posts: 827
Location: Kingston
Quote:
A study by researchers at the University of Virginia indicates the emerging use of a recombinant, or artificially produced, protein in diagnostic tests may not be a suitable replacement for the natural protein Ara h 1, one of the major peanut allergens.


Quote:
In allergy diagnostics, using a recombinant protein is thought to reveal more consistent results, as they are more homogenous than natural proteins. Individual protein molecules purified from a natural source show much more variation at a molecular level from one another,” says study co-leader Wladek Minor, professor of molecular physiology and biological physics in the School of Medicine.

“However, people are exposed to allergens from natural sources, not recombinant protein,” he continues, “and people develop antibodies to different fragments of natural allergens. If there is a significant difference between a natural source and the recombinant allergen used for allergy diagnosis, the recombinant allergen is not a good replacement in the test, because different types of allergies can be overlooked.”


http://www.futurity.org/health-medicine ... allergies/

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